Differences in Folate and Vitamin B12 Serum Levels Between Mothers Whose Children were Diagnosed with Non-syndromic Cleft Lip and Cleft Lip with Palate

Non-syndromic (NS) cleft lip (CL) and with palate (CLP) are abnormalities in the orofacial area that not accompanied by head neck have normal physical growth cognitive development. Cleft CLP caused two factors, genetic environmental factors which include deficiencies of micronutrients such as folate vitamin B12. This study aimed to determine differences B12 serum levels between mothers whose children were diagnosed NS CL CLP. An analytical observational was conducted on from 44 Data analyzed t-test for Mann Whitney levels. All non-syndromic CLP, respectively, had Meanwhile, most suffered deficiency, both (91.6%) (93.75%). The mean level slightly higher than (p-value = 0.711) but showed no statistical difference groups. median 0.394), indicated groups statistically significant. There palate.
 Keywords: Folate, B12, CL,